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Determination of optimal extraction conditions for phenolic compounds from Pistacia atlantica leaves using the response surface methodology

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dc.contributor.author Yousfi, Mohamed
dc.contributor.author Ben Ahmed, Ziyad
dc.contributor.author Viaene, Johan
dc.contributor.author Dejaegher, Bieke
dc.contributor.author Demeyer, Kristiaan
dc.contributor.author Mangelings, Debby
dc.contributor.author Heyden, Yvan Vander
dc.date.accessioned 2019-06-11T09:15:29Z
dc.date.available 2019-06-11T09:15:29Z
dc.date.issued 2016
dc.identifier.uri http://e-biblio.univ-mosta.dz/handle/123456789/10788
dc.description.abstract Response surface methodology in combination with a Box-Behnken experimental design was performed to optimize the extraction conditions, resulting in a maximum yield for the total phenolic content (TPC) from leaves of Pistacia atlantica. The ranges of the examined independent variables (factors), i.e. the extraction time (24-72 hours), liquid-to-solid ratio (30:1-50:1 ml solvent per g dry leaf) and extraction temperature (35-55°C) were identified by preliminary experiments. Quadratic polynomial regression models were fitted through the experimental results. They showed acceptable coefficients of multiple determination. From the models, the liquid-to-solid ratio was found to have the most influence on the extraction of TPC. The optimum extraction conditions were found at 72 h extraction time and 50:1 ml/g liquid-to-solid ratio. For the extraction temperature, rather high values (about 50°C) were found best. Using the optimized conditions, the TPC varied from 256 to 306 mg gallic acid equivalents g dry leaf in different sample types. en_US
dc.publisher Analytical Methods en_US
dc.subject Pistacia atlantica leaves en_US
dc.subject extraction optimization en_US
dc.subject phenolic compounds en_US
dc.subject BoxBehnken design en_US
dc.subject response surface methodology en_US
dc.title Determination of optimal extraction conditions for phenolic compounds from Pistacia atlantica leaves using the response surface methodology en_US
dc.type Article en_US


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