Résumé:
Faced with many failures in the elimination of CoNS pathogens, we aimed to find an effective agent to
eradicate these bacteria. In the present study we tested 20 isolates of CoNS collected from the Anti-Cancer
Center of Batna (Algeria). As antistaphylococcal agents we used in our experiment 29 Pseudomonas
isolates selected from the roots of plant (Hordeum murinum). The results of crossed streak method on
MHA medium showed that the 29 isolates of Pseudomonas inhibited 19 CoNS. The strain with the greater
inhibitory effect PK inhibited 14 CoNS. The high performing Pseudomonas PK has been used for the
production of phenazine compounds. The dry compound of PK from ethyl acetate extraction has been
shown to be effective against 13 isolates of staphylococci. The percentage of biofilm inhibition by the PK
phenazine extract was between (32.2%) and (77.56%). The analysis of the compound obtained by UVvisible and infrared spectrum showed that it was similar to hydroxyphenazine.
