Abstract:
Plant extracts are considered as an alternative therapy against microbial infections.
The bacterium P. aeruginosa is a multiresistant opportunistic pathogen in its
planktonic and biofilm forms.
In the present study methanol extract and two fractions of ethyl acetate and butanol
extracts prepared from leaves of Prunus persica were tested against three
Pseudomonas aeruginosa clinical isolates and reference strain (P . aeruginosa ATCC
27853). The results show an antibacterial activity against the strains tested by the
flavonoid extract extracted by butanol compared with the other two extracts. A
remarkable inhibitory activity was recorded. A MIC was a around 12.5mg / ml and an
MBC at a concentration of 25mg / ml.
The antibiofilm effect of butanol extract tested by the crystal violet method was
negative on the all four strains of P. aeruginosa.
