Résumé:
Molds are filamentous microscopic fungi that reproduce by spores, their development requires favorable conditions of temperature, nutrition and humidity. They can be both beneficial and harmful. And be sensitive to UV rays. In this study, we used a physical mutagen, namely the effect of UV radiation on Penicillium sp spores, isolated from rotten orange. Prolonge exposure to UV rays leads to sensitivity and death of fungal cells. Ultraviolet (UV) radiation, especially UV-C (wavelength 200 to 280 nm), has a well-know ermicidal efect. When a suspension of Penicillium sp spores is exposed to this type of radiation, several biological effects can be observed, depending on the dose (intensity and duration of exposure). UV exposure mainly results in damage to the DNA of the spores. These damages, often in the form of pyrimidine dimers, prevent correct DNA replication, leading to inhibition of germination or cell death. The longer the exposure time, the more pronounced the effect. Experimental studies show that UV exposure causes an exponential decrease in the number of viable spores. UV radiation represents an effective disinfection agent against Penicillium sp., disrupting their life cycle and germination capacity, making it a potential tool in microbiological control, particularly in food, hospital or pharmaceutical environments.