Résumé:
The objective of our work is realizing a prospective study on nephropathy’s complications
on diabetic patients, and to assess the biological and physiological parameters (to assess their
effectiveness for early diagnosis of renal disease and if they vary according to the degree of this
complication).
Within a part of the epidemiological investigation, 53 diabetics hospitalized patients, aged
between 17 and 76 years were recruited, they were classified into groups according to age, sex,
type of diabetes and degree of renal complication.
The second phase of our study is to make a biological assessment containing the following
blood parameters: glucose, creatinine, uric acid, urea, albumin, cholesterol and triglycerides.
Through our results, it appeared that creatinine is an effective biochemical parameter for
estimating the function and the degree of renal complication.
Unbalanced blood glucose in our patients is a real risk for the development of diabetes to
chronic renal failure and end stage.
Hypertension is poorly controlled, by the high percentage of hypertensive patients in our sample
compared into other studies; it is found in 86% of patients recruited and even affects young
subjects.
In our case the uremia and uric acid appear to be indicators of the severity of renal disease
and may be biological markers of prognosis.
The other parameters (cholesterol, albumin) except for triglycerides are fairly controlled by
diet and treatment, because the levels of these parameters are within the standards.
