THE EXPRESSION OF INOS IN MOUSE EXPERIMENTAL MODEL POINTS TO INFLAMMATORY CONDITIONS ASSOCIATED WITH PARKINSON’S DISEASE

dc.contributor.author	laiche, fatima
dc.contributor.author	djebli, Noureddine
dc.date.accessioned	2018-07-12T08:48:40Z
dc.date.available	2018-07-12T08:48:40Z
dc.date.issued	2015-07
dc.identifier.issn	1857 – 7881 (Print) e - ISSN 1857- 7431
dc.identifier.uri	http://hdl.handle.net/123456789/681
dc.description.abstract	Parkinson’s Disease (PD) is one of the most common neurodegenerative diseases. Several molecular mechanisms are involved. The objective of conducting this study was to evaluate the expression of iNOS in mouse experimental model of PD. PD was induced through injecting mice with 10 doses of MPTP (25 mg/kg) and probenecid (250 mg/kg). Mice in control group were injected by saline (25 mg/kg). Immunohistochemical stains for iNOS in brain sections were carried out using indirect immunoperoxidase techniques. Study findings showed that there was a significant difference in the expression level iNOS in study groups (P<0.001), and experimental PD group had more expressed iNOS levels compared with control group. Taken together, the present study confirmed the impact of induction of iNOS in the etiology of PD.	en_US
dc.language.iso	en	en_US
dc.publisher	European Scientific Journal	en_US
dc.relation.ispartofseries	;vol.11, No.21
dc.subject	Parkinson’s Disease (PD),mouse,MPTP,iNOS	en_US
dc.title	THE EXPRESSION OF INOS IN MOUSE EXPERIMENTAL MODEL POINTS TO INFLAMMATORY CONDITIONS ASSOCIATED WITH PARKINSON’S DISEASE	en_US
dc.type	Article	en_US

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