Abstract:
Objective: To search for further synergistic combinations of gentamicin and raw honey that
might have potential in treating wounds.
Methods: The antibacterial activity and synergistic interaction of raw honey and gentamicin
was assessed by using agar well diffusion method. Two Gram-negative (Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 2154) bacteria were selected for antibacterial activity assay. The cultures of bacteria were maintained in their appropriate agar slants at 4 °C throughout the study and used as stock cultures.
Results: Raw honey and gentamicin interacted synergistically to inhibit Escherichia coli and
Pseudomonas aeruginosa.
Conclusions: These results suggest that combinations of raw honey and gentamicin have
therapeutic benefits in prophylaxis of infections caused by multidrug-resistant Gram-negative
bacilli
