Applications of computational animal models in radiation therapy research

Abstract

In this chapter, we cover the usefulness and extent of performing computations using small animal models in cancer treatment with radiation therapy. Since mice are the most utilized animal models in cancer research, we restrict our discussion to the mouse model. The wide adoption of mice among other small animals is justified by their small size, in addition to the fact that they are inexpensive, easy to breed and to manipulate, reproduce rapidly, and can be genetically modified.