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Repérage des endophénotypes des parents d'enfants autistes

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dc.contributor.author Zouatine, Houcine
dc.contributor.author Mbarek, Mohammed El Amine
dc.date.accessioned 2019-10-09T10:07:14Z
dc.date.available 2019-10-09T10:07:14Z
dc.date.issued 2019-07-11
dc.identifier.uri http://e-biblio.univ-mosta.dz/handle/123456789/13021
dc.description.abstract Autism is a poorly known disability, but it is constantly increasing. The studies carried out in Algeria on the frequency of autism remain insufficient and do not allow an accurate assessment of the number of people with autism. Our study, conducted on a group of 67 parents of children with autism and a group of 59 normal parents in the region of Mostaganem, the relevance of a self-questionnaire for the characterization of a parental endophenotype, defined by the presence Significant "traits related" to autistic disorders two main factors, the first corresponding to the dimensions "socialization and communication", the second to dimensions "rigidity and imagination" The results of our survey indicate a male predominance, with a sex ratio of 2: 1 and. 51% of affected children are older and younger children. In addition, consanguinity associated with an increased risk of autism. We also confirm the results obtained in our study concerning the comparison between parents of children with autism and parents of the normal group on larger numbers, identifying a significant difference between the two groups for the factor "rigidity and imagination". Finally, we show that the scores obtained by the parents of autistic children and the normal parents evolve significantly between childhood and adulthood. In conclusion, the self-questionnaire FAQ for detecting endophenotypes associated with the autistic spectrum in parents of children with autism. This tool can be useful for characterizing the phenotype of relatives in genetic studies. en_US
dc.language.iso fr en_US
dc.subject Autism en_US
dc.subject Self-questionnaire en_US
dc.subject Endophénotyp. en_US
dc.title Repérage des endophénotypes des parents d'enfants autistes en_US
dc.type Other en_US


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