Antibacterial effects of raw extracts, aloïn, and phynolic compounds of Aloe Vera latex on different strains (Escherichia coli, Staphylococus aureus and Pseudomonas aeruginosa)

Abstract

The pharmacological potential of plants, especially Aloe Vera, a medicinal plant native to South and East Africa, traditionally and widely used for thousands of years, with numerous therapeutic properties, it has been considered a miracle plant. There are three parts in the leaf: the juice containing many anthraquinones, with laxative properties, the latex, and the gel which is healing, moisturizing, anti-inflammatory, anti-infectious, anti-allergic, anti-diabetic and even antiviral. These numerous components have been used in synergy for a long time, their effects confirmed by numerous scientific studies. In this context and taking into account the medicinal knowledge of the natives, we have outlined our objective which is to test the synergistic antibacterial effect of the polyphenols contained in the whole leaf against (Pseudomonas areuginosa, Staphylococcus aureus and Escherichia coli), and compare it with the same effect of the active molecules extracted from each part of the leaf separately. In this perspective, we proceeded to the extraction by maceration of each part separately and the whole leaf; which showed a yield of the PPs extracted with annonk method. Their antibacterial activities of the different extracts were estimated by inhibition on MH agar, and plotted diameters of inhibition showed significant sensitivity anti-bacterial effects with 11,5±2,355b of aloin diluted 50% against the E coli strains, and for the S aureus showed sensitive anti-bacterial effects with diameter 13,083±1,165b by the aloin pure in other hand P aeroginosa showed a resistant to all the PPs with diameter of initiation less then 7,5±4,964a in thynolic compounds of latest as the highest value .This reveals an antibacterial effect by bactericidal or inhibitory action very interesting. Aloe Vera present excellent alternatives to synthetic antibiotics to fight against bacterial infestations caused by E coli and S aureus, allowing us to face the problems of antibiotic resistance and the dramatic side effects of the excessive consumption of synthetic antibiotics. It is just important to underline that the use of the whole leaf is not without risk as toxicity problems have also been found.