évaluation des marqueurs biochimiques chez une population diabétobèses dans la région de Mostaganem

Abstract

Diabetes and obesity have reached such proportions in the world that we are talking about a pandemic. Both diseases are an important cause of mortality and multiple complications. Medical and financial issues make these two diseases a major public health problem. Type 1 diabetes is an auto-immune disease that leads to the destruction of insulin-secreting B cells and therefore requires an intensive optimised exogenous insulin therapy. Type 2 diabetes is a polygenic disease whose expression is favored by inadequate lifestyle, leading to obesity. It combines a relative insulin secretory defect and insulin resistance, the latter being associated with various other cardiovascular risk factors. Our work for goal to evaluate the biochemical markers at an obese population reached of diabetes in the region of Mostaganem. This study with carried on 40 subjects (20 witnesses and 20 patients obeses attacks of diabetes) old from 31 to 78 years, chosen in a completely random way. The results show that the rate of the values of the biochemical parameters at the obese population reached of diabetes is significantly higher than the witnesses. Thus the diabetes is strongly correlated with the years and the IMC. Treatment consists of lifestyle modifications first, then the prescription of various glucose-lowering oral drugs and finally, when requested, insulin therapy.#The prevention of diabetes and its complications is a major public health objective.