Étude descriptive et évaluation de quelques paramètres biochimiques chez des enfants et des adolescents atteints de diabètetype I dans la willaya de sidi bel Abbes.

Abstract

The aim of our work is to carry out a descriptive study on diabetes, its risk factors and some complications, and to evaluate its biological and pathophysiological parameters. As part of our epidemiological investigation and in a first phase, 68 children among them were 34 diabetic children aged 0 to 18 years were recruited. They were classified into groups according to age, sex, type of breastfeeding, diet and physical activity, and how to control blood glucose. And the degree of certain complication. In a second phase of our study, we performed a biological check-up with the following blood parameters: blood glucose, glycated hemoglobin, Total cholesterol, triglyceride, creatinine and urea, and liver function tests (TGO and TGP). According to our results, the characteristics studied that are significantly related to diabetes are age especially in the child stage, and consanguinity (38.22%), poorly balanced diet and lack of breastfeeding (14.71% ) Is followed by some complication such as hypertension (29.41%) and cardiovascular disease (14%). However, overweight is not significantly related to type 1 diabetes as risk factors, and even for other parameters such as cholesterol Almost identical with a slight increase in triglycerides, while creatinine values were stable with a noticeable increase in (26.47%). While the liver function study evaluated by the TGO and TGP assay did not record Disturbance for these parameters; also have the majority of patients with higher blood glucose levels, and an HbA1c greater than 6% in our patients. Finally, this study, which is a descriptive study, could be a valuable resource to evaluate the multidisciplinary approach and the impact of different strategies of disease prevention.