Effet antagoniste entre les bactéries lactiques et les germes pathogènes responsable des infections urinaires

Abstract

Lactic acid bacteria are well known for their probiotic properties and their ability to produce antimicrobial compounds such as lactic acid, bacteriocins, and hydrogen peroxide. Urinary tract infections (UTIs), mainly caused by Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, and Staphylococcus saprophyticus, represent a major public health concern due to their high prevalence and increasing antibiotic resistance. This study aimed to evaluate the antagonistic activity of Lactobacillus spp., Lactococcus lactis, and Streptococcus thermophilus against these uropathogenic bacteria. The antagonistic activity was assessed using in vitro microbiological tests. Among the strains studied, Lactococcus lactis exhibited the highest antagonistic activity against some pathogenic bacteria. The results demonstrated variable inhibitory effects depending on the bacterial strains tested, suggesting that lactic acid bacteria could serve as a promising natural alternative for the prevention and control of urinary tract infections.