Effet du jeun de ramadan sur l’évolution de certains paramètres biologiques chez les femmes diabétiques atteintes de maladies cardiovasculaires

Abstract

Most diabetics, especially female diabetics, die from cardiovascular complications. Chronic hyperglycemia often causes the formation of free radicals involved in LDL oxidation, which contributes to premature aging of the arteries and accelerates the process of atherosclerosis. Atherosclerosis is the cause of most cardiovascular events, such as stroke and heart attack. Our work was carried out in the internal medicine department of the hospital of Ain Tadeles-Mostaganem and aimed at monitoring the effect of fasting during Ramadan on variations in some biological parameters in diabetic women with cardiovascular complications. The study was conducted in 20 patients, aged 58 to 86 years, suffering from type 2 diabetes with cardiovascular complications (heart failure, stroke, and peripheral vascular disease). Measurements and controls were performed on the day before fasting and on the day of Ramadan and included: BMI, blood glucose, insulin, HbA1c, triglycerides, cholesterol, LDL, VLDL, protein, creatinemia and uremia. The results underwent a block analysis of variance and a comparison of means. Fasting in Ramadan appears to improve patients' glycosylated hemoglobin (HbA1c) levels as well as lipid profile, including especially plasma levels of triglycerides, cholesterol, LDL-c and HDL-c.