Fréquence des hémoglobinopathies au niveau du service d’hémobiologie de l’EPH Ain Tedles déterminées su Calpillarys periode 2017-2020

Abstract

Our work consisted of a retrospective study (from May 2017 to June 2020) performed on 150 cases of hemoglobinopathy diagnosed at the hemobiology service EPH-Ain Tedles. it offered a better understanding of hemoglobinopathies in our region by describing their epidemiological aspects The results obtained are: 280 cases have been diagnosed hemoglobinopathy: -thalassemia heterozygous:60,35% , B -thalassemia homozygous :2,14% Double heterozygous C/ } thalassemia; 1.07% Double heterozygous S / B thalassemia: 2.14% Sickle cell trait: 17.85%, Sickle cell disease :1.78%, Hemoglobin C/A 8,92% homozygous hemoglobin C :1,07, Hb S / C: 0.35% Hb O Arab heterozygous: 3.57% Hb S-O-Arab heterozygous :0.71%. -62.17% of cases are adults, 37.82% of the cases are children under 15 years old. -79 cases of patients were under 10 years old, 45 cases with ß-thalassemia heterozygous -Distribution of hemoglobinopathies approximately equal sex -Most patients resident in Mostaganem with 60 cases ß-thalassemia. -The Inbreeding was involved in 13.92% of cases; it is 50% in homozygous ß-thalassemia. -Heterozygous forms 91,71% majority are found especially after the age of 20 years -Among the composite forms: 50% S / B-thalassemia . -Homozygous and composite forms found mainly at the age of 6 months to 10 years _The main clinical signs found in each type of hemoglobinopathies are: pallor, jaundice, the SPMG/ HPMG.