L’intérêt du dosage de la vitamine D et l’hormone parathyroïdienne (PTH) dans le cas d’insuffisance rénale chronique

Abstract

Chronic renal failure (CRI) has become a public health problem due to its increasingly high frequency with the lengthening of life expectancy. Patients with chronic renal failure have a mortality that greatly exceeds the rate predicted by conventional cardiovascular risk factors. Vitamin D deficiency, highly prevalent in this population, is also independently associated with mortality. The objective of our study is to confirm the relationship between vitamin D and PTH during chronic kidney disease, through a descriptive epidemiological study conducted on 57 hemodialysis cases. Our results show that chronic renal failure is responsible for 1-alpha-hydroxylase deficiency, lower serum calcium, hyperphosphatemia, 1-25-dihydroxyvitamin D deficiency, and increased PTH release. , which will cause secondary hyperparathyroidism (HPTS).