Evaluation de l’effet thérapeutique d’une plante médicinale «Persil (Petroselinum sativum)» sur les paramètres biochimiques chez les patients atteints la lithiase urinaire.

Abstract

This experimental study focused on the effect of parsley tea (Petroselinum sativum) on patients with urinary lithiasis. Eleven volunteers, both men and women aged between 31 and 66 years, participated in the study. The analysis included two parts: an in vivo study by examining urine samples before and after a five-day parsley tea treatment, and an in vitro part focusing on kidney stone dissolution. The results revealed a clear improvement in urinary parameters after the treatment: increased urine volume, more alkaline pH, decreased density, and most notably, a significant reduction in crystalluria. In parallel, biochemical markers (urea, creatinine, uric acid, calcium) showed a tendency toward normalization. In vitro, the parsley extract enabled notable mass loss of certain stone types, especially calcium oxalate dihydrate and uric acid stones. These findings suggest that parsley tea exerts diuretic, alkalinizing, and litholytic effects, making it a promising natural approach for the prevention and treatment of kidney stones.