Résumé:
Hemophilia is an inherited bleeding disease with an X-linked method of transmission. This is a
relatively rare condition characterized by a deficiency of factor VIII (hemophilia A) or factor IX
(hemophilia B) of the coagulation.
The objective of this work, carried out at the level of the hemobiology laboratory of the
university hospital establishment (UHE) of Oran (from February 16 to March 16, 2020) was to
deepen our knowledge about hemophilia, and learn the diagnostic techniques used in routing,
which are: Prothrombin time (PT); Activated partial thromboplastin time (APTT) or Kaolin
partial thromboplastin time (KPTT) and F factor
We have collected 24 cases of hemophilia type A this period, with hemophilia B being very rare.
The average patient age was 12,1 years, the majority of patients were children from 1 to 16 years
old, constituting a rate of 69%, while patients aged between 24 years and 43 years old
represented only 26%. Determining the level of factor F enabled us to classify the type of
hemophilia into 60% severe, 30% minor and 10% moderate hemophilia.
PT values are disturbed (below standards) in 22 of 24 patients (91,7%) and APTT values are
disturbed (above standards) in all patients.
Treatment of hemophilia is complex and costly, and the best way to fight it is preventive health
education for patients and parents.
