Dosage de quelques marqueurs biologiques chez des patients diabétiques atteints d’une insuffisance rénale chronique avant et après hémodialyse

Abstract

Chronic renal failure is considered to be one of the most common complications in diabetics. The objective of our work is to conduct a study on kidney failure in diabetics, to evaluate its biological parameters and to estimate the effectiveness for the early diagnosis of kidney disease. Most patients were found to have diabetes, the leading cause of chronic renal failure and high blood pressure. The biological assessment of blood parameters of diabetic patients hemodialyzed by sex and age showed the effectiveness of hemodialysis. creatinine, urea, fasting glycemia, sodium, potassium Before hemodialysis almost all parameters had high levels: 87.3(mg/l) for creatinine, 1.46(g/l) for urea, 2.5(g/l) for blood sugar, 153.25(mmol/l) for blood sugar sodium and 7,5(mmol/l) for potassium. These values decrease after hemodialysis but remain high compared to normal, thus the levels recorded after hemodialysis are in the order of 65.17(mg/l) for creatinine, 1.16(g/l) for urea, 1.73(g/l) for blood sugar, 140.83(mmol) mol/l) for sodium and 5,9(mmol/l) for potassium. Our results show that creatinine and urea are biochemical parameters that are effective in estimating the function and degree of renal complication. Imbalanced blood sugar in our patients is a real risk factor for the development of diabetes into chronic and terminal renal failure. Hemodialysis is a treatment (HD) that addresses a vital need for urea patients that must be integrated into a long-term, global perspective. It aims to correct metabolic disorders, to ensure the survival of patients.