EFFET CURATIF DU LYCOPÈNE DE PASTÈQUE SUR LA PROSTATITE CHEZ LE RAT WISTAR

Abstract

The interest in lycopene is due to its antioxidant role and its strong curative potential against infections more precisely against prostatitis, it is in this context that we carried out the extraction of lycopene and the in-vivo study of its therapeutic effect based on a treatment of prostatitis caused by staphylococcus aureus in the wistar rat. Four weeks after instillation of staphylococcus, urine samples were taken. The 25 model rats (CBP) randomly divided into four groups were treated with either lycopene alone or lycopene / cefalexin, or cefalexin alone with a positive control. After two weeks of treatment, the urine samples collected were subjected to a urine culture in order to enumerate the existing bacteria and after sacrifices of the rats, the prostate was recovered for microbiological and histological tests. The results obtained show a significant reduction in the number of bacteria in the urine and in the prostate tissues in the rats of the group treated with lycopene combined with the antibiotic cefalexin.