Résumé:
Vitamin D is now experiencing a resurgence of interest, not only because of its
interesting bone effects in the prevention of osteoporotic fractures as its protean extra osseous
effects (reduction in the risk of cancer, inflammatory diseases and even mortality, etc.)
observed in large observational studies. Measuring 25-hydroxyvitamin D levels is now a very
reliable method of assessing individual stores
The objective of this work is to determine the prevalence of hypovitaminosis D in the
population of the Mostaganem region and its risk factors, to study the correlations between
the 25(OH) D level and demographic, clinical and biological parameters.
The 25 (OH) D levels were distinguished into 3 groups: normal dosage (≥ 30 ng / ml),
insufficiency (10 - 30 ng / ml) and deficiency (<10 ng / ml). The explanatory variables studied
were: age, body mass index, origin, sex, phototype, type of clothing.
This is a prospective epidemiological study including 120 volunteers of both sexes (94
women and 26 men) aged between 12 and 86 years. We tested for 25(OH) D, PTH and
calcium.
These are 120 patients with an average age of 51.27 years, the prevalence of
hypovitaminosis D (25-OH-D <29ug / l) is 86% in the general population 89% in women and
74% in men.
The analyzes objectified a correlation between the dosage of 25 (OH) and the sex and
the phototype such that a positive and significant correlation was found between the 25OHD
and the PTH (r = 0.27; p = 0.001). There was, however, no significant correlation between
25(OH) D level and serum calcium concentration.
The prevalence of 25 (OH) D deficiencies in the study population (86%) of the
Mostaganem region is a matter of concern for their future health. Our results underline the
importance of systematic supplementation in this particularly at-risk population.
